Olmetyle H 20 Tablet is a fixed-dose combination of two antihypertensive agents—Olmesartan Medoxomil and Hydrochlorothiazide—used for the effective management of high blood pressure (hypertension). Olmesartan is an angiotensin II receptor blocker (ARB) that lowers blood pressure by relaxing blood vessels, thereby improving blood flow and reducing strain on the heart. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps eliminate excess salt and water from the body through urine, which also contributes to lowering blood pressure. This combination is especially beneficial for patients whose blood pressure is not adequately controlled by monotherapy. The dual mechanism offers complementary benefits: Olmesartan reduces vasoconstriction, while Hydrochlorothiazide decreases blood volume. Together, they provide a more consistent and long-lasting antihypertensive effect. Olmetyle 20H is typically taken once daily and is known for its efficacy, good tolerability, and convenient dosing.
Common side effects of Olmetyle 20H may include dizziness, headache, fatigue, and gastrointestinal discomfort. Hydrochlorothiazide may cause increased urination, low potassium levels (hypokalemia), and mild dehydration. In some cases, patients may experience hypotension, elevated blood uric acid or blood sugar levels, and changes in kidney function. Rare side effects include allergic reactions, electrolyte imbalances, and photosensitivity. Regular monitoring of kidney function, blood pressure, and electrolytes may be advised during long-term use.
Olmetyle 20H Tablet is indicated for the treatment of essential hypertension in adults, particularly in patients whose blood pressure is not adequately controlled with Olmesartan or Hydrochlorothiazide alone. It helps in reducing the risk of cardiovascular events such as stroke and heart attack by maintaining optimal blood pressure levels.
Olmetyle 20H Tablet should only be used under medical supervision. It is not recommended during pregnancy, especially in the second and third trimesters, due to the risk of fetal toxicity. Caution is advised in patients with kidney or liver disease, diabetes, or electrolyte disturbances. Avoid concurrent use of potassium supplements, other diuretics, or NSAIDs unless directed by a physician. Regular monitoring of blood pressure, renal function, and serum electrolytes is important during therapy. Patients should not stop the medication abruptly and should maintain a healthy lifestyle including a balanced diet, reduced salt intake, and regular physical activity for optimal results.
Store Olmetyle 20H Tablet in a cool, dry place below 30°C. Protect it from light, heat, and moisture. Keep out of reach of children and pets. Do not use this medicine beyond the expiry date printed on the packaging.