Clickstin Dry Syrup is a pediatric oral formulation containing Colistin Sulphate, a potent, broad-spectrum antibiotic primarily used in the treatment of severe bacterial infections caused by multidrug-resistant (MDR) gram-negative organisms. It is especially useful when other antibiotics have failed or are contraindicated.
Colistin Sulphate acts by disrupting the bacterial cell membrane, resulting in the leakage of essential intracellular contents and ultimately leading to cell death. This makes it particularly effective against dangerous pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae—bacteria that are often resistant to other classes of antibiotics.
Clickstin Dry Syrup is formulated for reconstitution with sterile water and is intended for oral administration in pediatric patients. The syrup offers a convenient and effective way to deliver accurate doses of Colistin in children suffering from serious infections, including lower respiratory tract infections, urinary tract infections, gastrointestinal infections, and bloodstream infections due to susceptible organisms.
This formulation is especially useful in hospital or home care settings under strict medical supervision. Its liquid format ensures ease of administration and better compliance in children who may have difficulty swallowing tablets or capsules. Clickstin Dry Syrup is typically reserved for use in infections that have not responded to conventional antibiotic therapy, ensuring targeted and critical care in pediatric antibacterial management.
Given the rise in antibiotic resistance, Colistin has regained importance as a "last-resort" antibiotic. Therefore, its use should be carefully monitored to prevent resistance development and maintain its clinical efficacy. The addition of sterile water ensures a stable and accurate preparation of the syrup before administration.