IFOSIDE 1GM Injection: Ifosfamide IP 1 gm

The Alkylating Power: Mechanism and Role in Advanced Cancer Regimens

Key Indications: Sarcomas, Testicular Cancer, and Lymphomas

Critical Administration Note: The Necessity of Co-treatment with Mesna

PCD Pharma Franchise for Ifosfamide: High-Demand Injectable Oncology Segment
Quality Assurance: WHO-GMP Certified Production of IFOSIDE 1GM

Ifoside injection

Composition : Ifosfamide IP 1gm Injection

Dosage Form : Injection

Packaging Type : Vial

Packaging : 1gm

Price : ₹1/-

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IFOSIDE 1GM Injection (Ifosfamide IP 1 gm) is a potent alkylating antineoplastic agent widely used as a cornerstone in combination chemotherapy protocols for advanced and recurrent cancers. As a prodrug, Ifosfamide is metabolically activated in the liver by CYP450 enzymes into active metabolites (primarily isophosphoramide mustard) that form highly damaging DNA cross-links. This mechanism effectively inhibits DNA synthesis and repair, leading to cancer cell death.

Key Clinical Applications:

  • Testicular Germ Cell Tumors: Indicated specifically as a third-line chemotherapy agent.

  • Sarcomas: A vital component in treating Soft Tissue Sarcoma and Osteosarcoma (bone cancer).

  • Lymphomas and Others: Used in regimens for Non-Hodgkin's Lymphoma and certain refractory cases of Small Cell Lung Cancer and Ovarian/Cervical Cancer.

Important Safety Note: Ifosfamide metabolism produces the urotoxic metabolite Acrolein, which necessitates the mandatory co-administration of a uroprotectant agent like Mesna to prevent Hemorrhagic Cystitis. We ensure all partners are fully supported with educational and marketing materials detailing this crucial co-treatment protocol.

Partnering for the IFOSIDE 1GM PCD Pharma Franchise offers a chance to secure a monopoly in a highly specialized, recurring revenue segment of the oncology market, backed by WHO-GMP compliant quality and robust institutional demand.

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About the Product

IFOSIDE 1GM Injection (Ifosfamide IP 1 gm) is a potent alkylating antineoplastic agent widely used as a cornerstone in combination chemotherapy protocols for advanced and recurrent cancers. As a prodrug, Ifosfamide is metabolically activated in the liver by CYP450 enzymes into active metabolites (primarily isophosphoramide mustard) that form highly damaging DNA cross-links. This mechanism effectively inhibits DNA synthesis and repair, leading to cancer cell death.

Key Clinical Applications:

  • Testicular Germ Cell Tumors: Indicated specifically as a third-line chemotherapy agent.

  • Sarcomas: A vital component in treating Soft Tissue Sarcoma and Osteosarcoma (bone cancer).

  • Lymphomas and Others: Used in regimens for Non-Hodgkin's Lymphoma and certain refractory cases of Small Cell Lung Cancer and Ovarian/Cervical Cancer.

Important Safety Note: Ifosfamide metabolism produces the urotoxic metabolite Acrolein, which necessitates the mandatory co-administration of a uroprotectant agent like Mesna to prevent Hemorrhagic Cystitis. We ensure all partners are fully supported with educational and marketing materials detailing this crucial co-treatment protocol.

Partnering for the IFOSIDE 1GM PCD Pharma Franchise offers a chance to secure a monopoly in a highly specialized, recurring revenue segment of the oncology market, backed by WHO-GMP compliant quality and robust institutional demand.

May cause nausea, vomiting, fatigue, low blood counts, hair loss, and bladder irritation. Rarely, neurotoxicity, kidney toxicity, or severe infections may occur.

Soft tissue and bone sarcomas Lymphomas Testicular cancer Other solid tumors as per oncologist’s guidance

Administer only under strict medical supervision in a hospital or oncology setting. Blood counts, liver, kidney, and bladder function should be regularly monitored. Adequate hydration and protective agents may be required to prevent bladder toxicity. Report any neurological symptoms, unusual bleeding, or infections promptly.

Store below 25°C, protected from light. Keep out of reach of children. Use immediately after reconstitution as per medical instructions.

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